Bernard Bihari, MD
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Updated: May 18, 2010
Bernard Bihari, MD, was the discoverer of the clinical effects of LDN in humans. In his groundbreaking clinical trial of patients with HIV/AIDS at Downstate Medical Center in 1985-86, Bihari discovered the significant effectiveness of low dose naltrexone in protecting the battered immune systems of those who were infected. With that knowledge, he entered private practice in an attempt to counter the then untreatable disease.
BERNARD BIHARI, M.D.
Evarts EV, Bental E, Bihari B, Huttenlocher P. Spontaneous discharge of single neurons during sleep and waking. Science 1962; No. 3505, 135:726.
Bental E, Bihari B. Evoked activity of single neurons in sensory association cortex of the cat. J. Neurophys. 1963; 26:207.
Bihari B, Richman A, Moran D. Heroin addicts among servicemen. Presented at the 1972 Annual Meeting American Psychiatric Association. Scientific Proceedings in Summary Form 125th Annual Meeting, American Psychiatric Association 1972. Summary Paper No. 221:246-247.
Bihari B. Alcoholism in M.M.T.P. patients: Etiological factors and treatment approaches. From the Proceedings, Fifth National Conference on Methadone Treatment, Washington D.C. 1973; 1:288-295.
Bihari B. Alcoholism and methadone maintenance. Amer. J. Drug and Alcohol Abuse 1974; No. 1, 1:79-87.
Bihari B. Drug dependency: Some etiological considerations. Amer. J. Drug and Alcohol Abuse 1976; No. 3, 3:409-123.
Begleiter H, Porjesz B, Bihari B, Kissin B. Event-related brain potentials in boys at risk for alcoholism. Science 1984; 225:1493-1496.
Bihari B, Ottomanelli G, Drury F, Ragone V. Fluctuation of T-cell subsets in repeated measures in AIDS patients. Letter to the Editor, AIDS Res. 1986; No. 4, 2:263-265.
Bihari B, Drury F, Ragone V, Ottomanelli G, Buimovici-Klein E, Orbe M, Foeste W, Thomas J, Kirk R. Low-dose naltrexone in the treatment of AIDS. Submitted for publication.
Nightingale S, Cameron W, Gordin F, Sullam. PM, Cohn DL, Chaisson R, Eron LJ, Sparti PD, Bihari B, Kaufman DL, Stern JJ, Pearce DD, Weinberg WG, LaMarca A, Siegal FP. Two controlled trials of rifabutin prophylaxis against mycobacterium avium complex infection in AIDS. N. Eng. J. Med. 1993; No. 12, 329:828-833.
SELECTED PAPERS PRESENTED AT CONFERENCES
Bihari B, Drury F, Ragone VP, Orbe MG, Foeste WF, Thomas JR, Kirk RP, Buimovici-KIein E, Kokayi K. Low-dose naltrexone in the treatment of the immune deficiency in AIDS and ARC. Presented at the 11 International Conferenceon AIDS, Paris, France June 1986.
Bihari B, Drury F, Ragone VP, Ottomanelli GA, Buimovici-Klein, E, Orbe MG Foeste WF, Thomas JR, Kirk RP. Low-dose naltrexone in the treatment of AIDS. Presented. at the III International Conference on AIDS, Washington D.C., June 1987.
Bihari B, Drury F, Ragone VP, Ottomanelli GA, Buimovici-Klein E. Alpha interferon as a marker and a secondary pathogenic factor in AIDS Presented at the III International Conference on AIDS, Washington D.C.,. June 1987.
Bihari B, Martin J, Seaman D. The use of disulfiram as an immunomodulating agent. IV International Conference on AIDS, Stockholm, Sweden, June 1988.
Bihari B, Drury F, Ragone VP, Ottomanelli GA, McCoy J, Buimovici-Klein E. Low-dose naltrexone in the treatment of AIDS. Presented at the IV International Conference on AIDS, Stockholm, Sweden, June 1988.
Hittelman J, Willoughby A, Mendez H, Silcott J, Shah P, Holman S, Glass L, Bihari B, Goedert J, Landesman S. Prospective neurodevelopmental outcome of infants with perinatally acquired HIV infection and their controls. The American Pediatric Society Conference on AIDS, Washington, D.C., May 1989.
Bihari B, Drury F, Ragone VP, Ottomanelli GA, Cannon G, Buimovici-Klein E. Low dose naltrexone in the treatment of AIDS: Long term follow-up results. Presented at the V International Conference on AIDS, Montreal, Canada, June 6, 1989.
Bihari B, Ottomanelli G. Defense mechanisms and HIV related behaviors in substance abusers. Presented at the V International Conference on AIDS, Montreal, Canada, June 6, 1989.
Bihari B. Impact on AIDS clinical trials of the use of non-approved therapies. Presented at the V International Conference on AIDS, Montreal, Canada, June 6, 1989.
Bihari B, Plotnikoff N, Freeman K. et al. Methionine Enkephalin in the treatment of ARC, VII International Conference on AIDS, Florence, June 1991 (Poster WB2137).